Chu Xin-Yi, Chen Si-Ming, Zhao Ke-Wei, Tian Tian, Gao Jun, Zhang Hong-Yu
Hubei Key Laboratory of Agricultural Bioinformatics, College of Informatics, Huazhong Agricultural University, Wuhan 430070, China.
Life (Basel). 2021 Jul 24;11(8):738. doi: 10.3390/life11080738.
The debate on the temperature of the environment where life originated is still inconclusive. Metabolic reactions constitute the basis of life, and may be a window to the world where early life was born. Temperature is an important parameter of reaction thermodynamics, which determines whether metabolic reactions can proceed. In this study, the scale of the prebiotic metabolic network at different temperatures was examined by a thermodynamically constrained network expansion simulation. It was found that temperature has limited influence on the scale of the simulated metabolic networks, implying that early life may have occurred in a relatively wide temperature range.
关于生命起源的环境温度的争论仍无定论。代谢反应构成了生命的基础，可能是早期生命诞生的世界的一扇窗口。温度是反应热力学的一个重要参数，它决定了代谢反应能否进行。在本研究中，通过热力学约束的网络扩展模拟研究了不同温度下益生元代谢网络的规模。结果发现，温度对模拟代谢网络的规模影响有限，这意味着早期生命可能在相对较宽的温度范围内出现。
