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[脂质代谢紊乱与脂肪肝]

[Disturbances of lipid metabolism and fatty liver].

作者信息

Mach T

机构信息

Kliniki Gastroenterologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.

出版信息

Przegl Lek. 1999;56(3):205-10.

Abstract

Fatty liver (FL) is a frequently diagnosed liver disease. There are presented the etiological factors causing FL, including the most frequent alcohol, obesity, diabetes mellitus, hyperlipoproteinemias and drugs. There are discussed some disturbances of lipid metabolism leading to FL. Morphologically we can distinguish FL with large or small fatty droplets. The more severe kind of the disease is FL with hepatitis (steatohepatitis). Symptoms of FL are not characteristic, as well as there are absent typical changes in biochemical analyzes. There are presented methods of the liver visualization (USG, CT) used in the diagnostics of FL. Treatment of FL includes of the elimination of etiological factors first of all, there is still under debate the supportive action of pharmacotherapy in FL.

摘要

脂肪肝(FL)是一种常被诊断出的肝脏疾病。文中介绍了导致脂肪肝的病因,包括最常见的酒精、肥胖、糖尿病、高脂血症和药物。文中还讨论了一些导致脂肪肝的脂质代谢紊乱。在形态学上,我们可以区分大脂肪滴或小脂肪滴的脂肪肝。该疾病更严重的类型是伴有肝炎的脂肪肝(脂肪性肝炎)。脂肪肝的症状不具有特异性,生化分析中也没有典型变化。文中介绍了用于脂肪肝诊断的肝脏可视化方法(超声、CT)。脂肪肝的治疗首先包括消除病因,药物治疗在脂肪肝中的支持作用仍存在争议。

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