Mach T, Zahradnik-Bilska J
Kliniki Gastroenterologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1999;56(3):216-9.
Barretts esophagus (BE) is a disorder in which the normal squamous mucosa of the esophagus is replaced by columnar epithelium. Data from the literature of the last years show that BE with so-called specialized intestine type mucosa is a frequently diagnosed disease during endoscopical examination, particularly in men over 60 years of age with heartburn. This type of epithelium is a recognized risk factor of the esophageal adenocarcinoma. There is presented the current classification, pathogenesis, diagnosis and treatment of BE as well as the problem of the BE connection with the esophageal adenocarcinoma.
巴雷特食管(BE)是一种食管正常鳞状黏膜被柱状上皮取代的病症。过去几年的文献数据表明,具有所谓特殊肠型黏膜的BE是内镜检查中经常诊断出的疾病,尤其是在60岁以上有烧心症状的男性中。这种上皮类型是食管腺癌公认的危险因素。本文介绍了BE的当前分类、发病机制、诊断和治疗以及BE与食管腺癌的关联问题。