Szczepanik M, Gryglewski A, Solecki R
Katedry Immunologii, Collegium Medicum, Uniwersytetu Jagiellońskiego w Krakowie.
Przegl Lek. 1999;56(3):227-30.
There are many specialised defence mechanisms connected with immunity of peritoneal cavity. These are absorbtion of bacteria and their toxins from peritoneum, phagocytosis, opsonization, activation of the complement and separation of infection in the peritoneal cavity. A very important role in defence mechanisms of peritoneal cavity play GALT and PALT. Among many cells of the immune system mastocytes and gamma delta T cells have important role in induction and regulation of immune mechanisms in the peritoneal cavity. Lymphocytes T gamma delta release many cytokines and chemokines what allows them to play their protecting role during peritonitis. Released cytokines (especially IFN-gamma) activate macrophages to produce and secret many proinflammatory cytokines and factors. On the other hand mast cells play their role in defence of peritoneal cavity via TNF-alpha and histamine release and inhibition of fibrynolysis.
有许多与腹腔免疫相关的特殊防御机制。这些机制包括从腹膜吸收细菌及其毒素、吞噬作用、调理作用、补体激活以及腹腔内感染的隔离。肠道相关淋巴组织（GALT）和支气管相关淋巴组织（PALT）在腹腔防御机制中发挥着非常重要的作用。在免疫系统的众多细胞中，肥大细胞和γδT细胞在腹腔免疫机制的诱导和调节中发挥着重要作用。γδT淋巴细胞释放多种细胞因子和趋化因子，这使得它们在腹膜炎期间能够发挥保护作用。释放的细胞因子（尤其是γ干扰素）激活巨噬细胞，使其产生并分泌多种促炎细胞因子和因子。另一方面，肥大细胞通过释放肿瘤坏死因子-α（TNF-α）和组胺以及抑制纤维蛋白溶解在腹腔防御中发挥作用。
