Lapierre V, Hervé P
Unité de Médecine Transfusionnelle et d'Hémovigilance, Institut Gustave Roussy, Villejuif.
Presse Med. 1999;28(24):1336-40.
Safety in transfusion medicine involves all the different procedures designed to guarantee safe transfusion in accordance with standards established on the current scientific knowledge. It is thus crucial to continuously monitor scientific advances in order to transfer progress in fundamental research as rapidly as possible to transfusion applications and thus maintain the highest level of safety. RISK REDUCTION: The risk of residual viral contamination might be additionally reduced by the introduction of genomic screening. Several virus inactivation processes are currently under evaluation for products derived from blood cells. The risk of post-transfusion alloimmunization might be reduced by eliminating or masking antigens (immunogens). SUBSTITUTION PRODUCTS: There are several ongoing research and development programs concerning substitution products. Products under study include perfluocarbon emulsions, hemoglobin solutions, membrane fragments, and platelet substitutes.
