Payne B J, Saunders L Z
Vet Pathol. 1978 Aug;15 Suppl 5:51-87. doi: 10.1177/0300985878015s0507.
Heavy metal nephropathy is a pathologic entity of the renal tubular epithelium of rats, evoked by lead, gold, and other heavy metals. It is characterized acutely by coagulative necrosis, subacutely by cortical fibrosis, and chronically by cytomegaly and karyomegaly. Finally, adenomas develop, some of which become malignant.
重金属肾病是大鼠肾小管上皮的一种病理实体,由铅、金和其他重金属诱发。其急性特征为凝固性坏死,亚急性特征为皮质纤维化,慢性特征为细胞肿大和核肿大。最终会形成腺瘤,其中一些会恶变。