Deng D J, Yang S M, Li T, Xin H J
Beijing Institute for Cancer Research & Beijing Medical University School of Oncology, China.
Biomed Environ Sci. 1999 Mar;12(1):54-61.
N-(nitrosomethyl) urea (NMU) was characterized in the carcinogenic nitrosated fish sauce (NFS) with high performance liquid chromatography (HPLC)-photohydrolysis-pyrolysis-thermal energy analysis recently. We used HPLC-electronic spray ionization-mass spectrometry and HPLC-diode array detection to confirm NMU in NFS further. It was observed that the corresponding chromatographic fraction of NMU of NFS showed the same mass spectrum (m/z 64, 102, and 145) and ultraviolet-absorbance (lambda max = 230 nm) as those of authentic NMU. These results confirmed that the component of NFS was NMU.
N-（亚硝基甲基）脲（NMU）最近通过高效液相色谱（HPLC）-光水解-热解-热能分析在致癌性亚硝化鱼露（NFS）中得到了表征。我们使用HPLC-电喷雾电离质谱和HPLC-二极管阵列检测进一步确认了NFS中的NMU。观察到NFS中NMU的相应色谱馏分与真实NMU具有相同的质谱（m/z 64、102和145）和紫外吸收（最大吸收波长=230nm）。这些结果证实NFS的成分是NMU。
