Pearce J L, Luke R K, Bettelheim K A
Department of Agricultural Sciences, Faculty of Science, Technology and Engineering, La Trobe University, Bundoora, Melbourne, Australia.
FEMS Immunol Med Microbiol. 1999 Aug 1;25(1-2):137-44. doi: 10.1111/j.1574-695X.1999.tb01337.x.
This investigation is an extension of previous studies on the possible role of intestinal Escherichia coli in sudden infant death syndrome (SIDS) to include the isolation of extraintestinal E. coli. The lungs of 52 and the blood of 144 SIDS infants were cultured and isolates were investigated. E. coli was isolated from about a quarter of post-mortem lung samples and about 15% of blood samples from SIDS infants. The isolates were subjected to microbiological studies, including serotyping and haemolysin assays. The majority were found to belong to serogroups commonly associated with bacteraemia. These results may indicate that extraintestinal E. coli plays a role in SIDS.
本研究是先前关于肠道大肠杆菌在婴儿猝死综合征（SIDS）中可能作用的研究的扩展，包括分离肠外大肠杆菌。对52例SIDS婴儿的肺部和144例SIDS婴儿的血液进行培养，并对分离株进行研究。从约四分之一的尸检肺样本和约15%的SIDS婴儿血液样本中分离出大肠杆菌。对分离株进行了微生物学研究，包括血清分型和溶血素检测。发现大多数分离株属于通常与菌血症相关的血清群。这些结果可能表明肠外大肠杆菌在SIDS中起作用。
