Luceno V
Rev Laryngol Otol Rhinol (Bord). 1999;120(2):103-9.
The authors reports a case of inverted papilloma in a man of 59. The presenting symptom was unilateral nasal obstruction which developed over a period of five years. The characteristic feature of inverted papillomas is slow local growth with a tendency to cause absorption of bone and to recur, and also a potential for malignant change. Treatment is only surgical, and consists of wide and complete local excision to avoid recurrence, using either the para-latero-nasal approach or a degloving technique. The etio-pathogenesis of inverted papillomas is probably viral. DNA of papillomavirus origin has been identified in the cells of an inverted papilloma by using techniques of in situ hybridisation.
作者报告了一例59岁男性的内翻性乳头状瘤病例。主要症状是单侧鼻塞，持续了五年。内翻性乳头状瘤的特征是局部生长缓慢，有导致骨质吸收和复发的倾向，并且有恶变的可能。治疗仅采用手术方式，包括广泛而彻底的局部切除以避免复发，可采用鼻侧切开术或掀翻术。内翻性乳头状瘤的病因发病机制可能与病毒有关。通过原位杂交技术，已在一例内翻性乳头状瘤的细胞中鉴定出乳头瘤病毒来源的DNA。
