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[钙离子和蛋白激酶C在维生素E对中性粒细胞呼吸爆发及淋巴细胞增殖转化作用中的角色]

[Role of Ca ions and protein kinase C in the action of vitamin E on respiratory burst of neutrophils and blast transformation of lymphocytes].

作者信息

Kapralov A A

机构信息

Research Institute of Physiology of Taras Schevchenko Kiev University.

出版信息

Ukr Biokhim Zh (1978). 1998 Sep-Oct;70(5):64-8.

Abstract

It was shown that vitamin E decreased the stimulating role of oxidative burst activators which influenced on Ca(2+)-dependent mechanisms (A23187, verapamil, FMLP). Jointly addition of this vitamin and blood plasma contained tocopherol-binding proteins influenced on mechanisms associated with protein kinase C. It was shown that Ca ions can also take part in tocopherol's action on blast transformation of lymphocytes.

摘要

结果表明,维生素E降低了氧化爆发激活剂的刺激作用,这些激活剂影响钙依赖机制(A23187、维拉帕米、FMLP)。这种维生素与含有生育酚结合蛋白的血浆共同添加会影响与蛋白激酶C相关的机制。结果表明,钙离子也可能参与生育酚对淋巴细胞增殖转化的作用。

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