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扩散张量成像在导致神经元和轴突损伤疾病中的临床应用。

Clinical use of diffusion-tensor imaging for diseases causing neuronal and axonal damage.

作者信息

Uluğ A M, Moore D F, Bojko A S, Zimmerman R D

机构信息

Department of Radiology, Cornell University Medical College-New York Presbyterian Hospital, NY 10021, USA.

出版信息

AJNR Am J Neuroradiol. 1999 Jun-Jul;20(6):1044-8.

Abstract

Diffusion-tensor imaging is an emerging technique that can supply microscopic structural information about tissue in vivo. With this technique it is possible to measure the amount of anisotropy of water diffusion within tissues and to assess the degree to which directionally ordered tissues have lost their normal integrity. This study was performed in four patients to evaluate the feasibility of applying this technique in clinical situations in which there is known or suspected damage to white matter tracts.

摘要

扩散张量成像(Diffusion-tensor imaging)是一种新兴技术,它能够在活体状态下提供有关组织的微观结构信息。借助该技术,可以测量组织内水扩散的各向异性程度,并评估方向性有序组织丧失其正常完整性的程度。本研究对4例患者进行,以评估在已知或怀疑存在白质束损伤的临床情况下应用该技术的可行性。

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