促红细胞生成素的促红细胞生成、神经营养和血管生成功能以及促红细胞生成素产生的调节

Erythropoietic, neurotrophic, and angiogenic functions of erythropoietin and regulation of erythropoietin production.

作者信息

Masuda S, Nagao M, Sasaki R

机构信息

Division of Applied Life Sciences, Graduate School of Agriculture, Kyoto University, Japan.

出版信息

Int J Hematol. 1999 Jul;70(1):1-6.

PMID:10446487

Abstract

Stimulation of erythrocyte formation has been generally thought to be the sole physiological function of erythropoietin. Erythropoietin and its receptors, however, are also expressed in the central nervous system. In addition, erythropoietin is produced in the uterus in an estrogen-dependent manner. Novel functions of erythropoietin in these local sites are presented.

摘要

红细胞生成素的刺激作用通常被认为是促红细胞生成素的唯一生理功能。然而，促红细胞生成素及其受体也在中枢神经系统中表达。此外，促红细胞生成素在子宫中以雌激素依赖的方式产生。本文介绍了促红细胞生成素在这些局部部位的新功能。