Brown R N, Di Luzio L, Gomes C, Nicolaides K H
The Harris Birthright Research Centre for Fetal Medicine, King's College Hospital School of Medicine, Denmark Hill, London, United Kingdom.
J Ultrasound Med. 1999 Aug;18(8):543-6. doi: 10.7863/jum.1999.18.8.543.
In 342 singleton pregnancies in which the patients were undergoing chorionic villus sampling at 11 to 14 weeks of gestation, color Doppler sonography was used to obtain waveforms from the umbilical cord. The prevalence of pulsatile flow in the umbilical vein was higher in the 18 fetuses with trisomy 18 or 13 (16 of 18; 88.9%) than in the 18 fetuses with trisomy 21 (6 of 18; 33.3%) or the 302 chromosomally normal fetuses (73 of 302; 24.2%).
在342例单胎妊娠中，患者于妊娠11至14周接受绒毛取样，采用彩色多普勒超声获取脐带血流波形。18例18三体或13三体胎儿的脐静脉搏动血流发生率（18例中的16例，88.9%）高于18例21三体胎儿（18例中的6例，33.3%）或302例染色体正常胎儿（302例中的73例，24.2%）。
