Medina S, Valero-Fuenmayor N, Chacín-Bonilla L, Añez F, Giraldoth D, Arias J, Espina G, Achong A Y, Bonilla E
Department of Neurobiology, INBIOMED-FUNDACITE-ZULIA, Maracaibo, Venezuela.
Neurochem Res. 1999 Jun;24(6):775-8. doi: 10.1023/a:1020735730869.
When mice infected with the Venezuelan equine encephalomyelitis (VEE) virus were exposed to 2500 lux with a 12 h light: 12 h dark photoperiod, the serum levels of melatonin (MLT) remained constantly elevated. In mice exposed to 400 lux low levels of serum MLT were detected during the day and high levels during the night. An increase in the survival rate of the infected mice from 6 to 13 days after virus inoculation was also observed. The significant increment in the concentration of serum MLT produced by the high intensity light could be responsible for the longer survival rate of mice infected with the VEE virus.
当感染委内瑞拉马脑炎（VEE）病毒的小鼠暴露于光照强度为2500勒克斯、光周期为12小时光照：12小时黑暗的环境中时，褪黑素（MLT）的血清水平持续升高。在暴露于400勒克斯光照的小鼠中，白天检测到低水平的血清MLT，夜间则检测到高水平的血清MLT。还观察到病毒接种后6至13天感染小鼠的存活率有所提高。高强度光照导致血清MLT浓度显著增加，这可能是感染VEE病毒的小鼠存活率延长的原因。
