Kumar R, Sharma K H, Chhabra D K
Department of Neurosurgery, Sanjay Gandhi Postgraduate Institute of Medical Sciences, Lucknow, India.
Neurol India. 1999 Jun;47(2):145-7.
A 15 year old male, who had earlier been operated for intraspinal intramedullary ependymoma, subsequently developed a right cerebello pontine (CP) angle mass. A diagnosis of right CP angle ependymoma was considered, in view of established histology of previously operated spinal lesion. Histopathological examination of the well defined extra-axial mass, which was attached with ninth cranial nerve, however revealed a schwannoma. A diagnosis of Neurofibromatosis-2 (NF2) is strongly suspected, because of well established fact, that the spinal ependymomas may have association with lower cranial nerve schwannomas in NF2. Cranial and spinal MRI screening for early diagnosis of associated, asymptomatic lesions, in suspected cases of NF2, particularly in children, is recommended.
一名15岁男性，曾因脊髓内室管膜瘤接受手术，随后出现右侧桥小脑角肿块。鉴于先前手术的脊髓病变已确定的组织学，考虑诊断为右侧桥小脑角室管膜瘤。然而，对与第九颅神经相连的边界清晰的轴外肿块进行组织病理学检查，结果显示为神经鞘瘤。由于已明确的事实，即脊髓室管膜瘤可能与神经纤维瘤病2型（NF2）中的低位颅神经鞘瘤有关，因此强烈怀疑为NF2。对于疑似NF2的病例，尤其是儿童，建议进行头颅和脊髓MRI筛查，以早期诊断相关的无症状病变。
