Moriarty A
Birmingham Children's Hospital NHS Trust, UK.
Paediatr Anaesth. 1999;9(5):423-7. doi: 10.1046/j.1460-9592.1999.00395.x.
To try to decrease the incidence of side-effects associated with postoperative extradural infusions of local anaesthetics in combination with opioids, we have used plain ropivacaine solutions in 200 children. The first 72 children received an infusion of bupivacaine 0.125% + diamorphine 20 microg x ml-1, then 200 children received plain ropivacaine solutions. The children who received ropivacaine were found to have lower incidences of nausea, pruritus, urinary retention, and were less sedated, despite comparable analgesia. The management of plain ropivacaine for extradural analgesia is discussed.
为降低术后硬膜外输注局部麻醉药与阿片类药物联合使用相关的副作用发生率,我们对200名儿童使用了单纯罗哌卡因溶液。前72名儿童接受了0.125%布比卡因+20微克/毫升二氢吗啡酮的输注,然后200名儿童接受了单纯罗哌卡因溶液。尽管镇痛效果相当,但接受罗哌卡因的儿童恶心、瘙痒、尿潴留的发生率较低,且镇静作用较轻。本文讨论了单纯罗哌卡因用于硬膜外镇痛的管理。