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脊椎动物光感受器光适应的分子机制。

Molecular mechanisms of vertebrate photoreceptor light adaptation.

作者信息

Pugh E N, Nikonov S, Lamb T D

机构信息

FM Kirby Center for Molecular Ophthalmology, Department of Ophthalmology, Institute of Neurological Sciences, Stellar-Chance Laboratories, University of Pennsylvania, 422 Curie Boulevard, Philadelphia, Pennsylvania 19104-6069, USA.

出版信息

Curr Opin Neurobiol. 1999 Aug;9(4):410-8. doi: 10.1016/S0959-4388(99)80062-2.

Abstract

An important recent advance in the understanding of vertebrate photoreceptor light adaptation has come from the discovery that as many as eight distinct molecular mechanisms may be involved, and the realization that one of the principal mechanisms is not dependent on calcium. Quantitative analysis of these mechanisms is providing new insights into the nature of rod photoreceptor light adaptation.

摘要

最近在对脊椎动物光感受器光适应的理解方面取得的一项重要进展,来自于发现可能涉及多达八种不同的分子机制,以及认识到其中一种主要机制不依赖于钙。对这些机制的定量分析正在为视杆光感受器光适应的本质提供新的见解。

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