Moppett J, Haddadin I, Foot A B
The Royal Hospital for Sick Children St Michael's Hill Bristol BS2 8BJ.
Arch Dis Child Fetal Neonatal Ed. 1999 Sep;81(2):F134-7. doi: 10.1136/fn.81.2.f134.
Over nine years, 33 children with neonatal neuroblastoma were registered with the UKCCSG (United Kingdom Children's Cancer Study Group). Tumours of all stages were found, but stage 4S disease predominated. Five tumours were detected prenatally by ultrasonography. Treatment varied according to tumour stage. The overall survival of the group was 91%. Ten children have had long term complications as a result of their disease, usually as a result of spinal tumour involvement. The good overall prognosis in this age group is encouraging, but the poor neurological outcome of patients with intraspinal extension is of concern.
在九年时间里,英国儿童癌症研究组(UKCCSG)登记了33例新生儿神经母细胞瘤患儿。各期肿瘤均有发现,但以4S期疾病为主。5例肿瘤通过超声在产前被检测到。治疗根据肿瘤分期而异。该组患儿的总生存率为91%。10名儿童因疾病出现了长期并发症,通常是由于脊髓肿瘤受累。这个年龄组总体预后良好令人鼓舞,但脊髓内扩展患者的神经学结局不佳令人担忧。