Crespo J, de las Heras B, Rivero M, Lozano J L, Fábrega E, Pons-Romero F
Gastroenterology and Hepatology Unit, Faculty of Medicine, University Hospital Marqués de Valdecilla, Santander, Spain.
Postgrad Med J. 1999 Mar;75(881):159-60. doi: 10.1136/pgmj.75.881.159.
Aplastic anaemia complicating hepatitis is a rare but well-documented phenomenon; however in many patients the cause remains unknown. We present a 24-year-old man with a well-defined community-acquired hepatitis, probably due to hepatitis G virus (HGV), who developed severe aplastic anaemia. In this case, the absence of other agents likely to cause the clinical manifestations, and the detection of HGV RNA at the time of illness, clearly point to this agent as being responsible for both the hepatitis and the aplastic anaemia. Further studies in serial serum samples and meticulous evaluation of the disorders associated with the infection will be needed to prove or dispute a causal association of HGV and aplastic anaemia.
再生障碍性贫血并发肝炎是一种罕见但有充分文献记载的现象；然而，许多患者的病因仍不明。我们报告一名24岁男性，患有明确的社区获得性肝炎，可能由庚型肝炎病毒（HGV）引起，随后发展为严重再生障碍性贫血。在该病例中，不存在其他可能导致临床表现的病原体，且在患病时检测到HGV RNA，这明确表明该病原体是导致肝炎和再生障碍性贫血的病因。需要对系列血清样本进行进一步研究，并对与感染相关的病症进行细致评估，以证实或反驳HGV与再生障碍性贫血之间的因果关系。
