Loya F
Howard Hughes Medical Institute-National Institutes of Health Research Scholars Program, National Heart, Lung, and Blood Institute, Hematology Branch, USA.
Tex Med. 1996 Dec;92(12):68-73.
As many as 10% to 20% of presumed viral hepatitis cases are serologically non-A-E. Recently, two groups of investigators independently isolated a viral agent that may contribute to non-A-E viral hepatitis. This virus, named hepatitis G or GB virus C (HGV/GBV-C), is present in about 2% of accepted US blood donations. This paper reviews both the details involving isolation of the virus and the current epidemiological data, and shows that the accumulated evidence to date does not support the claim that HGV/GBV-C is responsible for non-A-E viral hepatitis.
在疑似病毒性肝炎病例中,多达10%至20%的病例血清学检查结果为非甲-戊型肝炎。最近,两组研究人员分别独立分离出一种可能导致非甲-戊型病毒性肝炎的病毒因子。这种病毒被命名为庚型肝炎病毒或GB病毒C型(HGV/GBV-C),在美国约2%的合格献血者中存在。本文回顾了该病毒分离的详细情况以及当前的流行病学数据,并表明迄今为止积累的证据并不支持HGV/GBV-C导致非甲-戊型病毒性肝炎这一说法。