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微创放射性引导甲状旁腺切除术

Minimally invasive radioguided parathyroidectomy.

作者信息

Costello D, Norman J

机构信息

Department of Surgery, University of South Florida School of Medicine, USA.

出版信息

Surg Oncol Clin N Am. 1999 Jul;8(3):555-64.

Abstract

The last decade has been characterized by an emphasis on minimizing interventional techniques, hospital stays, and overall costs of patient care. It is clear that most patients with sporadic HPT do not require a complete neck exploration. We now know that a minimal approach is appropriate for this disease. Importantly, the MIRP technique can be applied to most patients with sporadic HPT and can be performed by surgeons with modest advanced training. The use of a gamma probe as a surgical tool converts the sestamibi to a functional and anatomical scan eliminating the need for any other preoperative localizing study. Quantification of the radioactivity within the removed gland eliminates the need for routine frozen section histologic examination and obviates the need for costly intraoperative parathyroid hormone measurements. This radioguided technique allows the benefit of local anesthesia, dramatically reduces operative times, eliminates postoperative blood tests, provides a smaller scar, requires minimal time spent in the hospital, and almost assures a rapid, near pain-free recovery. This combination is beneficial to the patient whereas helping achieve a reduction in overall costs.

摘要

过去十年的特点是强调尽量减少介入技术、住院时间和患者护理的总体成本。显然,大多数散发性原发性甲状旁腺功能亢进症患者不需要进行完整的颈部探查。我们现在知道,对于这种疾病,采用微创方法是合适的。重要的是,微创甲状旁腺切除术(MIRP)技术可应用于大多数散发性原发性甲状旁腺功能亢进症患者,并且接受过适度高级培训的外科医生即可实施。使用γ探测器作为手术工具可将甲氧基异丁基异腈(sestamibi)转变为功能和解剖扫描,从而无需进行任何其他术前定位研究。对切除腺体中的放射性进行定量分析,无需进行常规冰冻切片组织学检查,也无需进行昂贵的术中甲状旁腺激素测量。这种放射性引导技术具有局部麻醉的优势,可显著缩短手术时间,无需术后血液检查,切口更小,住院时间最短,几乎可确保快速、几乎无痛的恢复。这种组合对患者有益,同时有助于降低总体成本。

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