Bowerman B, Shelton C A
Institute of Molecular Biology, 1370 Franklin Blvd, University of Oregon, Eugene, Oregon 97403, USA.
Curr Opin Genet Dev. 1999 Aug;9(4):390-5. doi: 10.1016/S0959-437X(99)80059-8.
Beginning with the first mitotic division in a Caenorhabditis elegans embryo, asymmetric cleavages establish much of the body plan. Although they share a common axis of polarity, at least three kinds of asymmetric cell division occur: two are under intrinsic control, while a third requires an inductive signal and may operate repeatedly throughout development.
从秀丽隐杆线虫胚胎的第一次有丝分裂开始,不对称分裂奠定了大部分的身体结构。尽管它们共享一个共同的极性轴,但至少发生三种不对称细胞分裂:两种受内在控制,而第三种需要诱导信号,并且可能在整个发育过程中反复起作用。