“感受压力”：门控机械敏感通道的结构洞察
'Feeling the pressure': structural insights into a gated mechanosensitive channel.
作者信息
Spencer R H, Chang G, Rees D C
机构信息
Howard Hughes Medical Institute, Division of Chemistry and Chemical Engineering, 147-75CH, California Institute of Technology, Pasadena, CA 91125, USA.
出版信息
Curr Opin Struct Biol. 1999 Aug;9(4):448-54. doi: 10.1016/S0959-440X(99)80063-3.
Abstract
The structure determination of the large-conductance mechanosensitive channel (MscL) from Mycobacterium tuberculosis has revealed the architecture of the first full-length, gated pentameric ion channel. This structure provides insights into the elements participating in the conductance and gating mechanisms of these channels.
摘要
结核分枝杆菌中大电导机械敏感通道（MscL）的结构测定揭示了首个全长、带门控的五聚体离子通道的结构。该结构为参与这些通道的电导和门控机制的元件提供了见解。
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