Spencer R H, Chang G, Rees D C
Howard Hughes Medical Institute, Division of Chemistry and Chemical Engineering, 147-75CH, California Institute of Technology, Pasadena, CA 91125, USA.
Curr Opin Struct Biol. 1999 Aug;9(4):448-54. doi: 10.1016/S0959-440X(99)80063-3.
The structure determination of the large-conductance mechanosensitive channel (MscL) from Mycobacterium tuberculosis has revealed the architecture of the first full-length, gated pentameric ion channel. This structure provides insights into the elements participating in the conductance and gating mechanisms of these channels.
结核分枝杆菌中大电导机械敏感通道（MscL）的结构测定揭示了首个全长、带门控的五聚体离子通道的结构。该结构为参与这些通道的电导和门控机制的元件提供了见解。
