通过细针穿刺活检诊断间变性大细胞淋巴瘤，包括多灶性骨KI-1淋巴瘤。

Diagnosis of anaplastic large-cell lymphoma, including multifocal osseous KI-1 lymphoma, by fine-needle aspiration biopsy.

作者信息

Liu K, Dodd L G, Osborne B M, Martinez S, Olatdioye B A, Madden J F

机构信息

Division of Cytopathology, Department of Pathology, Duke University Medical Center, Durham, North Carolina 27710, USA.

出版信息

Diagn Cytopathol. 1999 Sep;21(3):174-9. doi: 10.1002/(sici)1097-0339(199909)21:3<174::aid-dc6>3.0.co;2-q.

DOI:10.1002/(sici)1097-0339(199909)21:3<174::aid-dc6>3.0.co;2-q

PMID:10450102

Abstract

We present the fine-needle aspiration (FNA) findings of 4 cases of anaplastic (Ki-1) large-cell lymphoma (ALCL). A primary diagnosis of ALCL was made on FNA material in 2 cases, of which one was a multifocal osseous Ki-1 lymphoma. In the other 2 patients who had a known history of ALCL, FNA was used to detect recurrent disease. In all cases, large discohesive pleomorphic cells in the absence of lymphoglandular bodies in the background raised the possibility of a nonhematopoietic neoplasm. Immunochemical staining for CD30 was positive in all cases. The cytomorphologic and immunochemical features are discussed, along with the differential diagnosis of Ki-1 lymphoma. Diagn. Cytopathol. 1999;21:174-179.

摘要

我们报告了4例间变性（Ki-1）大细胞淋巴瘤（ALCL）的细针穿刺抽吸（FNA）结果。2例通过FNA材料做出了ALCL的初步诊断，其中1例为多灶性骨Ki-1淋巴瘤。另外2例有已知ALCL病史的患者，FNA用于检测复发性疾病。在所有病例中，背景中缺乏淋巴腺小体的大的离散多形性细胞提示了非造血性肿瘤的可能性。所有病例中CD30免疫化学染色均为阳性。本文讨论了其细胞形态学和免疫化学特征，以及Ki-1淋巴瘤的鉴别诊断。《诊断细胞病理学》1999年；21:174 - 179。