Liptay M J, Fry W A
Northwestern University Medical School, Section of Thoracic Surgery, Evanston Northwestern Healthcare, IL 60201, USA.
Semin Thorac Cardiovasc Surg. 1999 Jul;11(3):278-84. doi: 10.1016/s1043-0679(99)70069-9.
Malignant bone tumors constitute only 0.2% of all tumors. Bone sarcomas occur at a rate approximately one tenth that of sarcomas of the soft tissue. Malignant bone tumors of the chest wall and sternum are even more rare because most bone tumors occur in the long bones or joints. Because of the relative paucity of experience treating these malignancies, progress in successful therapies has been limited. Chondrosarcomas remain the most common bony malignant chest wall lesions and are discussed elsewhere in this issue. Other lesions in descending order of incidence include Ewing's sarcoma, osteosarcoma, malignant fibrous histiocytoma, solitary plasmacytoma, and Askin tumors. This article reviews these remaining five malignant bony chest wall tumors, along with their symptoms, presentations, and current approaches to therapy.
恶性骨肿瘤仅占所有肿瘤的0.2%。骨肉瘤的发病率约为软组织肉瘤的十分之一。胸壁和胸骨的恶性骨肿瘤更为罕见,因为大多数骨肿瘤发生在长骨或关节。由于治疗这些恶性肿瘤的经验相对较少,成功治疗的进展有限。软骨肉瘤仍然是最常见的胸壁骨恶性病变,在本期其他地方进行讨论。发病率由高到低的其他病变包括尤因肉瘤、骨肉瘤、恶性纤维组织细胞瘤、孤立性浆细胞瘤和阿斯金瘤。本文综述了其余五种胸壁骨恶性肿瘤,以及它们的症状、表现和当前的治疗方法。