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[过敏性紫癜:98例临床流行病学分析]

[Schönlein-Henoch syndrome: clinical-epidemiological analysis of 98 cases].

作者信息

Sticca M, Barca S, Spallino L, Livio L, Longhi R

机构信息

Unita Operativa di Pediatria, Ospedale Sant'Anna di Como.

出版信息

Pediatr Med Chir. 1999 Jan-Feb;21(1):9-12.

Abstract

We analyzed the clinical and epidemiological data of 98 patients (50 males and 48 females) aged between 6 months and 16 years, hospitalized for Schönlein-Henoch syndrome in the last 20 years. The incidence was higher during spring time. Throat culture was positive for streptococcus pyogenes in 16% of patients. 14 of 60 (23%) had a positive allergometric response to various tests. The extrarenal manifestations were: purpura (100%), articular (68%) or gastrointestinal (32%) involvement and orchitis (10%). Renal symptoms were observed in 23% of the patients, but a clear nephropathy was documented just in 5% of the cases, with resolution within 2 years. Our data suggest, in agreement with the letterature, that renal involvement in Schönlein-Henoch syndrome has usually a benign course.

摘要

我们分析了过去20年中因过敏性紫癜住院的98例年龄在6个月至16岁之间的患者(50例男性和48例女性)的临床和流行病学数据。春季发病率较高。16%的患者咽拭子培养出化脓性链球菌。60例患者中有14例(23%)对各种检测的变应原反应呈阳性。肾外表现为:紫癜(100%)、关节受累(68%)或胃肠道受累(32%)以及睾丸炎(10%)。23%的患者出现肾脏症状,但仅5%的病例记录有明确的肾病,且在2年内缓解。我们的数据与文献一致,表明过敏性紫癜的肾脏受累通常病程良性。

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