Mao C, Sato J, Matsuura M, Seto K
PUMC Hospital, Beijing.
Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 1997 Dec;19(6):436-41.
This study was performed to compare the efficacy of guided tissue regeneration (GTR) around dental implants immediately placed into extraction sockets by resorbable or nonresorbable membranes.
Mandibular P2, P3, and P4 of four adult beagle dogs were extracted bilaterally, and buccal standard defects were created and measured. Eighteen commercially pure titanium Steri-Oss implant fixtures were placed into the fresh extraction sockets. Four untreated implants were as controls, four implants received polytetrafluoroethylene (e-PTFE, Gore-Tex) membranes, five implants received collagen membranes, and five implants received polyglactin 910 mesh. After 14 weeks, clinical measurements were taken and the dogs were sacrificed and all specimens retrieved for histologic and histomophometric evaluation.
The average gain in bone height was 2.1 mm for untreated control sites, 3.3 mm for Gore-Tex sites, 3.8 mm for collagen sites, and 1.3 mm for polyglactin 910 sites.
The results of this study indicated that Gore-Tex and collagen membrane produced good results for GTR around implants. Collagen membrane can be a valid alternative to Gore-Tex membrane to improve bone regeneration around dental implants, while polyglactin 910 mesh seemed not suitable to be used as GTR membrane in immediate implantation for its high infection rate.
本研究旨在比较可吸收或不可吸收膜引导组织再生(GTR)技术在即刻植入拔牙窝的牙种植体周围的疗效。
对4只成年比格犬双侧拔除下颌P2、P3和P4牙,制作并测量颊侧标准骨缺损。将18颗商业纯钛Steri-Oss种植体植入新鲜拔牙窝。4颗未处理的种植体作为对照,4颗种植体覆盖聚四氟乙烯(e-PTFE,Gore-Tex)膜,5颗种植体覆盖胶原膜,5颗种植体覆盖聚乙醇酸910网。14周后进行临床测量,处死动物并取出所有标本进行组织学和组织形态计量学评估。
未处理对照部位的平均骨高度增加2.1mm,Gore-Tex部位为3.3mm,胶原膜部位为3.8mm,聚乙醇酸910部位为1.3mm。
本研究结果表明,Gore-Tex膜和胶原膜在种植体周围GTR中效果良好。胶原膜可作为Gore-Tex膜的有效替代品,用于改善牙种植体周围的骨再生,而聚乙醇酸910网因感染率高似乎不适用于即刻种植中的GTR膜。