Lorenzoni M, Pertl C, Keil C, Wegscheider W A
Department of Prosthodontics, School of Dentistry, University of Graz, Austria.
Int J Oral Maxillofac Implants. 1998 Sep-Oct;13(5):639-46.
In this clinical study, a bioabsorbable membrane (Biofix) and two augmentation membranes made of expanded polytetrafluoroethylene (Gore-Tex) were tested for their osteopromotive potential. Forty-six implants were augmented with Gore-Tex membranes, 45 implants with titanium-reinforced Gore-Tex membranes, and 38 peri-implant defects with a resorbable polyglycolid membrane (Biofix). Autogenous bone (n = 85) and bovine bone matrix (Bio-Oss, n = 16) were used as filling materials beneath membranes. The results showed that bone repair is significantly improved by the use of membrane techniques. The average rate of bone regeneration with non-resorbable membranes was 84% (GTAM) and 81% (TR-GTAM). The use of Biofix membranes resulted in an average bone gain of 60%. The differences in efficacy established for the three types of membranes were found to be statistically significant (P < .001). Barrier membranes represent a valid technique for the treatment of peri-implant defects. Clinical and histologic results showed that Bio-Oss is an osteoconductive scaffold that promotes new bone formation.
在这项临床研究中，对一种可生物吸收膜（Biofix）和两种由膨体聚四氟乙烯制成的增强膜（Gore-Tex）的骨促进潜力进行了测试。46颗种植体用Gore-Tex膜增强，45颗种植体用钛增强的Gore-Tex膜增强，38处种植体周围缺损用可吸收聚乙醇酸膜（Biofix）处理。自体骨（n = 85）和牛骨基质（Bio-Oss，n = 16）用作膜下填充材料。结果表明，使用膜技术可显著改善骨修复。不可吸收膜的平均骨再生率为84%（GTAM）和81%（TR-GTAM）。使用Biofix膜导致平均骨增量为60%。发现三种类型膜的疗效差异具有统计学意义（P <.001）。屏障膜是治疗种植体周围缺损的有效技术。临床和组织学结果表明，Bio-Oss是一种促进新骨形成的骨传导支架。
