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食蟹猴实验性视网膜中央动脉阻塞的急性期和晚期研究。I. 直流记录的视网膜电图的强度-振幅关系,特别提及c波。

Studies on acute and late stages of experimental central retinal artery occlusion in the Cynomolgus monkey. I. Intensity-amplitude relations of the D.C. recorded ERG with special reference to the c-wave.

作者信息

Textorius O, Nilsson S E, Skoog K O

出版信息

Acta Ophthalmol (Copenh). 1978;56(4):648-64. doi: 10.1111/j.1755-3768.1978.tb01377.x.

DOI:10.1111/j.1755-3768.1978.tb01377.x
PMID:104542
Abstract

The main positive component of the c-wave of the ERG is generated by the pigment epithelium-receptor complex, which is supplied from the choroidal circulation. Occlusion of the central retinal artery (OCRA) causes serious morphological damage only to the inner retina. An effect on the c-wave is therefore not primarily to be expected. In this study on five Cynomolgus monkeys with unilateral, laser-induced OCRA the c-wave was decreased, slightly in the early stage and markedly in the late stage. A hypothetical explanation of the reduced c-wave amplitude, involving changes in potassium ion concentration, is discussed. The conflicting results in other reports may be explained by uncontrolled influence of slow c-wave amplitude oscillations, by differences between acute and late stages, and by possible surgical damage to the choroidal circulation in some cases.

摘要

视网膜电图(ERG)的c波主要正向成分由色素上皮-感受器复合体产生,该复合体由脉络膜循环供血。视网膜中央动脉阻塞(OCRA)仅会对视网膜内层造成严重的形态学损伤。因此,预计其对c波不会产生主要影响。在这项针对五只单侧激光诱导性OCRA的食蟹猴的研究中,c波降低,早期降低程度较轻,晚期降低明显。本文讨论了一种关于c波振幅降低的假说性解释,该解释涉及钾离子浓度的变化。其他报告中相互矛盾的结果可能是由于c波振幅缓慢振荡的不受控制影响、急性和晚期之间的差异以及某些情况下脉络膜循环可能受到的手术损伤所致。

相似文献

1
Studies on acute and late stages of experimental central retinal artery occlusion in the Cynomolgus monkey. I. Intensity-amplitude relations of the D.C. recorded ERG with special reference to the c-wave.食蟹猴实验性视网膜中央动脉阻塞的急性期和晚期研究。I. 直流记录的视网膜电图的强度-振幅关系,特别提及c波。
Acta Ophthalmol (Copenh). 1978;56(4):648-64. doi: 10.1111/j.1755-3768.1978.tb01377.x.
2
Studies on acute and late stages of experimental central retinal artery occlusion in the Cynomolgus monkey. II. Influence on the cyclic changes in the amplitude of the c-wave of the ERG and in the standing potential of the eye.食蟹猴实验性视网膜中央动脉阻塞的急性期和晚期研究。II. 对视网膜电图c波振幅和眼静息电位周期性变化的影响。
Acta Ophthalmol (Copenh). 1978;56(4):665-76. doi: 10.1111/j.1755-3768.1978.tb01378.x.
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The c-wave of the human electroretinogram in central retinal artery occlusion.视网膜中央动脉阻塞时人类视网膜电图的c波
Acta Ophthalmol (Copenh). 1978 Oct;56(5):827-36. doi: 10.1111/j.1755-3768.1978.tb06647.x.
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Retinal pigment epithelial dysfunction in human immunodeficiency virus-infected patients with cytomegalovirus retinitis.感染人类免疫缺陷病毒且患有巨细胞病毒性视网膜炎患者的视网膜色素上皮功能障碍
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[Pattern and light electroretinograms in branch occlusions of the central retinal artery].[视网膜中央动脉分支阻塞时的图形和光视网膜电图]
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[Electroretinography and electrooculography in ischemic retinopathy].
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[The relationship between amplitude and extent of detachment indicated by the ERG c-wave of rabbit eyes with experimental retinal detachment].[实验性视网膜脱离兔眼视网膜电图c波所显示的脱离幅度与范围之间的关系]
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Electroretinographic changes and choroidal defects in a case of central retinal artery occlusion.
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Acute obstruction of the retinal and choroidal circulations.视网膜和脉络膜循环的急性阻塞
Ophthalmology. 1986 Nov;93(11):1373-82. doi: 10.1016/s0161-6420(86)33555-3.

引用本文的文献

1
Animal Models Used to Simulate Retinal Artery Occlusion: A Comprehensive Review.用于模拟视网膜动脉阻塞的动物模型:全面综述。
Transl Vis Sci Technol. 2019 Aug 15;8(4):23. doi: 10.1167/tvst.8.4.23. eCollection 2019 Jul.
2
Effects of intraocular irrigation with melatonin on the c-wave of the direct current electroretinogram and on the standing potential of the eye in albino rabbits.褪黑素眼内灌注对白化兔直流电视网膜电图c波及眼静息电位的影响。
Doc Ophthalmol. 1987 Jan;65(1):97-111. doi: 10.1007/BF00162725.
3
Cases reported at the FAN club meeting, Bonn, November 1984. Case 1: A case of preretinal neovascularization after retinal artery occlusion.
Int Ophthalmol. 1985 Nov;8(4):211-6. doi: 10.1007/BF00137648.