Angermeyer M C, Matschinger H
Klinik und Poliklinik für Psychiatrie Universität Leipzig.
Psychiatr Prax. 1999 Jul;26(4):171-4.
The present study is based on the assumption that for patients' compliance with psychotropic medication is also of importance their closest relatives' attitude towards that treatment.
In the context of a mail survey of relatives of people with schizophrenia, we asked what the relatives considered to be the most important positive and negative effects of the medication.
As expected, the main benefit was seen in the reduction of symptoms and in the prevention of relapse. In addition, the improvement of social adaptation and the subjective quality of life of the patients were also cited as important positive effects. Beside these effects which are closely related to the treatment of the disorder, respondents mentioned effects which can help to facilitate their living together with their ill relative. Among the side effects regarded as particularly unpleasant for the patients, sedation ranked first, followed by weight gain and extra-pyramidal motor symptoms.
The results are contrasted with those of a comparable study of people with schizophrenia.
本研究基于这样一种假设，即患者对精神药物治疗的依从性与其最亲近亲属对该治疗的态度同样重要。
在对精神分裂症患者亲属进行的邮件调查中，我们询问亲属认为药物最重要的积极和消极影响是什么。
正如预期的那样，主要益处在于症状减轻和预防复发。此外，患者社会适应能力的改善和主观生活质量的提高也被视为重要的积极影响。除了这些与疾病治疗密切相关的影响外，受访者还提到了有助于他们与患病亲属共同生活的影响。在被认为对患者特别不利的副作用中，镇静作用位居榜首，其次是体重增加和锥体外系运动症状。
将这些结果与一项针对精神分裂症患者的类似研究结果进行了对比。
