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[无糖尿病视网膜病变症状的I型糖尿病患者的对比敏感度]

[Contrast sensitivity in type I diabetics without symptoms of diabetic retinopathy].

作者信息

Liska V

机构信息

Ocní oddĕlení Nemocnice, Litomysl.

出版信息

Cesk Slov Oftalmol. 1999 Jul;55(4):237-45.

Abstract

UNLABELLED

The objective of the work was to assess whether in patients with IDDM without signs of diabetic retinopathy changes in the sensitivity function to contrast (CS) develop as compared with a group of healthy subjects matched for age but also as a result of the persistence of IDDM or the level of its long-term compensation investigated by means of glycated haemoglobin (HbA1c). CS was examined by the static method using a VCTS 6500 table from a distance of 208 and 420 cm which covered the spatial frequencies from 1.15 to 27.25 c/st. Moreover the authors assessed the best correctable central visual acuity on Snellen's optotypes, the ophthalmoscopic finding on the fundus with a colour photograph, fluorescein angiography and the HbA1c serum level. A group of 49 patients with IDDM was divided into two age groups: A(under 35 years), B (35 years and above). A marked decline of the CS function occurs in all spatial frequencies in both age groups. On comparison of the persistence of IDDM in group B no significant difference was found in CS, while in group A statistical significance was revealed in spatial frequencies 4 and 27.25 c/st. On comparison of the CS function in diabetics with a normal and pathological HbA1c level it was found that long-term hyperglycaemia has not a marked effect on visual functions.

CONCLUSION

The decline of CS in patients with IDDM without signs of diabetic retinopathy is influenced in particular by the patient's age, in junior patients also by the persistence of IDDM. Examination of the CS is a simple non-invasive method suitable for screening of early affections of the eyes in IDDM.

摘要

未标记

本研究的目的是评估在无糖尿病视网膜病变体征的胰岛素依赖型糖尿病(IDDM)患者中,与年龄匹配的健康受试者相比,对比敏感度(CS)功能是否会发生变化,同时评估IDDM的病程或通过糖化血红蛋白(HbA1c)研究的长期血糖控制水平对其的影响。使用VCTS 6500检查表,在208和420厘米的距离处通过静态方法检查CS,该检查表涵盖了1.15至27.25周/度的空间频率。此外,作者评估了Snellen视力表上的最佳矫正中心视力、眼底的检眼镜检查结果及彩色照片、荧光素血管造影和HbA1c血清水平。49例IDDM患者被分为两个年龄组:A组(35岁以下),B组(35岁及以上)。两个年龄组在所有空间频率上CS功能均显著下降。比较B组IDDM的病程,CS无显著差异,而A组在空间频率4和27.25周/度上具有统计学意义。比较正常和病理HbA1c水平的糖尿病患者的CS功能发现,长期高血糖对视觉功能无显著影响。

结论

无糖尿病视网膜病变体征的IDDM患者CS下降尤其受患者年龄影响,年轻患者还受IDDM病程影响。CS检查是一种简单的非侵入性方法,适用于筛查IDDM患者的早期眼部病变。

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