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艾滋病患者巨细胞病毒相关性视网膜脱离的无硅油手术修复

Surgical repair of cytomegalovirus-related retinal detachment without silicone oil in patients with AIDS.

作者信息

Canzano J C, Morse L S, Wendel R T

机构信息

Department of Ophthalmology, University of California, Davis, USA.

出版信息

Retina. 1999;19(4):274-80. doi: 10.1097/00006982-199907000-00001.

Abstract

PURPOSE

To analyze visual and anatomic results following surgical repair of cytomegalovirus (CMV)-related retinal detachment (RD) without silicone oil permanent tamponade.

METHODS

We analyzed five consecutive patients (six eyes) with acquired immunodeficiency syndrome and CMV-related RD that were repaired with pars plana vitrectomy with peeling of the posterior hyaloid, laser photocoagulation, encircling scleral buckle, and intraocular gas tamponade.

RESULTS

Preoperative vision ranged from 20/40 to hand motion. Total retinal reattachment was achieved in five of six eyes (83%). Macular reattachment was achieved in all eyes. Mean postoperative visual acuity was 20/40 (range 20/30-20/60). Mean postoperative follow-up was 12 months (range 7-19 months). All patients in this series presented with low preoperative CD4+ T-lymphocyte counts (mean, 24 cells per microL) and received highly active antiretroviral therapy. One retina (Patient 1) redetached 7 months after initial repair and was successfully reattached without using silicone oil. Postoperatively, visual acuity remains 20/30, and total retinal reattachment has been maintained for 16 months.

CONCLUSION

Good anatomic and visual success can be achieved and maintained in CMV-related RD without the use of silicone oil.

摘要

目的

分析在不使用硅油永久性填塞的情况下,巨细胞病毒(CMV)相关视网膜脱离(RD)手术修复后的视觉和解剖学结果。

方法

我们分析了连续5例获得性免疫缺陷综合征合并CMV相关RD患者(6只眼),采用经平坦部玻璃体切除术,联合后玻璃体后脱离剥除、激光光凝、环扎巩膜扣带术及眼内气体填塞进行修复。

结果

术前视力范围为20/40至手动。6只眼中有5只(83%)实现了视网膜完全复位。所有眼睛均实现了黄斑复位。术后平均视力为20/40(范围20/30 - 20/60)。术后平均随访时间为12个月(范围7 - 19个月)。该系列所有患者术前CD4 + T淋巴细胞计数均较低(平均每微升24个细胞),并接受了高效抗逆转录病毒治疗。1例视网膜(患者1)在初次修复后7个月再次脱离,未使用硅油成功复位。术后视力保持在20/30,视网膜完全复位已维持16个月。

结论

在不使用硅油的情况下,CMV相关RD可实现并维持良好的解剖学和视觉效果。

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