Terasaki H, Miyake Y, Mori M, Suzuki T, Kondo M
Department of Ophthalmology, Nagoya University School of Medicine, Japan.
Retina. 1999;19(4):302-8. doi: 10.1097/00006982-199907000-00006.
To study the fluorescein angiographic appearance of the extreme peripheral retina in patients with proliferative diabetic retinopathy with rubeosis iridis.
Using a modified endoscope, fluorescein angiography was performed prospectively during pars plana vitrectomy on 14 eyes of 12 patients with proliferative diabetic retinopathy who had or developed postoperative rubeosis. These findings were compared with those obtained from 41 eyes of 35 patients without rubeosis.
A fibrovascular ridge was observed at the ora serrata in 11 of 12 eyes (92%) with rubeosis but in only 15 of 35 (43%) eyes without rubeosis. Seven of 12 (58%) eyes with rubeosis showed the continuous type of fibrovascular ridge, whereas only 5 of 35 (14%) eyes without rubeosis showed the continuous type. A broom-shaped continuous fibrovascular ridge was observed only in eyes with rubeosis.
Many eyes with proliferative diabetic retinopathy showed unusual findings in the extreme retinal periphery, which were more frequent in the eyes with rubeosis iridis. Fluorescein angiography of this region may provide valuable information for possible anterior neovascularization.
研究伴有虹膜红变的增殖性糖尿病视网膜病变患者极周边视网膜的荧光素血管造影表现。
使用改良的内窥镜，对12例患有增殖性糖尿病视网膜病变且术后发生或出现虹膜红变的患者的14只眼，在玻璃体切割术中进行前瞻性荧光素血管造影。将这些结果与35例无虹膜红变患者的41只眼的结果进行比较。
12例有虹膜红变的眼中，11例（92%）在锯齿缘处观察到纤维血管嵴，而35例无虹膜红变的眼中只有15例（43%）观察到。12例有虹膜红变的眼中，7例（58%）表现为连续性纤维血管嵴，而35例无虹膜红变的眼中只有5例（14%）表现为连续性纤维血管嵴。仅在有虹膜红变的眼中观察到扫帚状连续性纤维血管嵴。
许多增殖性糖尿病视网膜病变患者的极周边视网膜表现出异常发现，在伴有虹膜红变的眼中更常见。该区域的荧光素血管造影可能为前部新生血管形成提供有价值的信息。
