病毒诱导的神经退行性疾病。
Viral-induced neurodegenerative disease.
作者信息
Buchmeier M J, Lane T E
机构信息
The Scripps Research Institute, 10550 North Torrey Pines Road, CVN-8, La Jolla, CA 92037, USA.
出版信息
Curr Opin Microbiol. 1999 Aug;2(4):398-402. doi: 10.1016/s1369-5274(99)80070-8.
Abstract
Viral etiology has been postulated in a variety of neurological diseases in humans, including multiple sclerosis. Several experimental animal models of viral-induced neurodegenerative disease provide insight into potential host- and pathogen-dependent mechanisms involved in the disease process. Two such mouse models are the Theiler's murine encephalomyelitis virus (TMEV) infection and mouse hepatitis virus (MHV) infection.
摘要
病毒病因已被推测与包括多发性硬化症在内的多种人类神经疾病有关。几种病毒诱导的神经退行性疾病的实验动物模型为了解疾病过程中潜在的宿主和病原体依赖性机制提供了线索。两种这样的小鼠模型是泰勒氏鼠脑脊髓炎病毒（TMEV）感染和小鼠肝炎病毒（MHV）感染。
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