Bulava G V, Abakumov M M, Druzenko O A, Markova O A, Pogodina A N, Khvatov V B
Khirurgiia (Mosk). 1999(7):35-9.
The results of treatment of 131 victims with penetrating wounds of the thorax complicated by profuse bleeding, are presented. 36 of them after surgery to prevent pyogenous complications received 5 injections of leukinferon (test group); 95 patients who were not treated by leukinferon made up control group comparable with the test group by sex, age and character of wounds. Comparative analysis of the results showed that treatment with leukinferon has resulted in decrease of postoperative complications. In the test group the number of complications made up 47.2%, in control group--61%. Al the same time in the former group there was only one pyogenous complication (2.9%), while in control group--10 (10.6%). After the course of leukinferon leucocytic formula of the blood has become normal, the number of patients with immunodeficiency and imbalance of proteins markers of the acuteness of inflammatory process has decreased.
本文介绍了131例胸部穿透伤并伴有大量出血患者的治疗结果。其中36例患者术后为预防化脓性并发症接受了5次白细胞干扰素注射（试验组）；95例未接受白细胞干扰素治疗的患者组成对照组，该组在性别、年龄和伤口特征方面与试验组具有可比性。结果的对比分析表明，白细胞干扰素治疗可减少术后并发症。试验组并发症发生率为47.2%，对照组为61%。同时，试验组仅出现1例化脓性并发症（2.9%），而对照组有10例（10.6%）。经过白细胞干扰素疗程后，血液白细胞计数恢复正常，免疫缺陷患者数量以及炎症过程急性期蛋白质标志物失衡情况有所减少。
