Yukioka H, Hayashi M, Yamada T, Fujimori M
Division of Critical Care Medicine, Osaka City University Medical School, Japan.
Eur J Emerg Med. 1999 Jun;6(2):161-4. doi: 10.1097/00063110-199906000-00015.
A 55-year-old man developed acute respiratory failure, pulmonary hypertension and left heart failure due to acute myocardial infarction. Nitric oxide (NO) inhalation improved arterial oxygenation, decreased pulmonary arterial pressure and increased cardiac output (CO), but combined use of dobutamine with NO produced increases in pulmonary arterial pressure and pulmonary capillary wedge pressure (PCWP). In this patient, amrinone decreased pulmonary arterial pressure and PCWP, and increased PaO2/FiO2 effectively while increasing CO. Combined use of inhaled NO and intravenous amrinone may have beneficial effects for a patient with acute respiratory and cardiac failure.
一名55岁男性因急性心肌梗死出现急性呼吸衰竭、肺动脉高压和左心衰竭。吸入一氧化氮（NO）改善了动脉氧合，降低了肺动脉压并增加了心输出量（CO），但多巴酚丁胺与NO联合使用会导致肺动脉压和肺毛细血管楔压（PCWP）升高。在该患者中，氨力农降低了肺动脉压和PCWP，并在增加CO的同时有效提高了PaO2/FiO2。吸入NO与静脉注射氨力农联合使用可能对急性呼吸和心力衰竭患者有益。
