用于支持激光多普勒灌注测量的组织中光散射的多普勒蒙特卡罗模拟。

Doppler Monte Carlo simulations of light scattering in tissue to support laser-Doppler perfusion measurements.

作者信息

de Mul F F, Steenbergen W, Greve J

机构信息

University of Twente, Department of Applied Physics, Enschede, The Netherlands.

出版信息

Technol Health Care. 1999;7(2-3):171-83.

PMID:10463306

Abstract

Doppler Monte Carlo (DMC) simulations of the transport of light through turbid media, e.g., tissue, can be used to predict or to interpret measurements of the blood perfusion of tissue by laser-Doppler perfusion flowmetry. We describe the physical and mathematical background of Doppler Monte Carlo calculations, and present some comparisons with measurements, performed with experimental flow models, built to mimic skin tissue characteristics and for the calibration of perfusion instruments,which are important goals of the Biomed-I concerted action. The measurements deal with coherence effects.

摘要

通过浑浊介质（如组织）的光传输的多普勒蒙特卡罗（DMC）模拟，可用于预测或解释通过激光多普勒血流仪对组织血液灌注的测量结果。我们描述了多普勒蒙特卡罗计算的物理和数学背景，并与使用实验血流模型进行的测量进行了一些比较，这些模型是为模拟皮肤组织特征和校准灌注仪器而构建的，这是生物医学 - I联合行动的重要目标。这些测量涉及相干效应。