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组织运动——激光多普勒血流信号中的一种干扰?

Tissue motion--a disturbance in the laser-Doppler blood flow signal?

作者信息

Oberg P A

机构信息

Department of Biomedical Engineering, Linköpings Universitet, Sweden.

出版信息

Technol Health Care. 1999;7(2-3):185-92.

PMID:10463307
Abstract

The tissue matrix in the human body is continuously in motion driven by forces generated by the circulatory and respiratory systems. The linear velocities recorded can be as high as 300 microm/s. The question raised: is the motion of tissue matrix generating an error signal in laser-Doppler (LD) recordings that is misinterpreted as solely a blood flow signal. The problem is studied by using a physical model demonstrating the contribution from a flow channel and, in addition, from a linear motion of the flow tube. Measurements of skin motion in the forearm have been performed. The corresponding spectra have been compared with blood flow spectra recorded with the LD method at the same sites. The two types of spectra overlap each other indicating that motion induced signals can be interpreted as a flow signal. The "blood flow" contribution from tissue motion varies strongly with the site studied.

摘要

人体组织基质在循环系统和呼吸系统产生的力的驱动下持续运动。记录到的线速度可达300微米/秒。由此提出的问题是:组织基质的运动是否会在激光多普勒(LD)记录中产生一个被误判为仅仅是血流信号的误差信号。通过使用一个物理模型来研究这个问题,该模型展示了来自流动通道以及流动管线性运动的贡献。已经对前臂皮肤运动进行了测量。相应的光谱已与在相同部位用LD方法记录的血流光谱进行了比较。这两种光谱相互重叠,表明运动诱导信号可被解释为血流信号。组织运动产生的“血流”贡献因研究部位的不同而有很大差异。

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