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孤立性棘球蚴囊肿——肺部圆形病灶的罕见病因

[The solitary echinococcal cyst--a rare cause of a round pulmonary focus].

作者信息

Gessner C, Wittig K, Griebsch G, Hoheisel G, Schauer J

机构信息

Abteilung Pneumologie, Medizinische Klinik und Poliklinik, Universität Leipzig.

出版信息

Dtsch Med Wochenschr. 1999 Jul 30;124(30):891-5. doi: 10.1055/s-2007-1024448.

Abstract

HISTORY AND ADMISSION FINDINGS

A 29-year-old man from Kazakhstan presented with right-sided chest pain, cough, whitish sputum and a temperature up to 38.5 degrees C. He had been working in an animal farm for the previous two years.

INVESTIGATIONS

Laboratory tests showed increased inflammatory parameters (WBC 15.9 gpt/l with an increased proportion of band and segmented granulocytes, C-reactive protein (242.3 mg/dl). Chest radiogram showed an infiltration and effusion in the right base judged to be due to pneumonia. In addition there was a round homogeneous mass, 2.5 cm in diameter, at the lateral thoracic wall in the 8th lower lobe segment. Computed tomography (CT) of the lung and mediastinum confirmed these findings. Bronchoscopy, echocardiography, upper abdominal sonography and CT of the skull revealed no other space-occupying lesion.

DIAGNOSIS, TREATMENT AND COURSE: The right-sided pneumonia was successfully treated, at first with ceftriaxone (i.v.), later with ofloxacin (by mouth). An echinococcal cyst was considered especially because of the patient's profession in Kazakhstan in the differential diagnosis of the right-sided round mass and confirmed by an indirect haemagglutination test giving an antibody titre of 1:1024. In response a thoracotomy was performed and the mass, histologically an echinococcal cyst (E. granulosa), resected. There were no other cysts. There was no explanation for the right-sided pneumonia.

CONCLUSIONS

Even though Echinococcosis is rare in Central Europe, it should be included in the differential diagnosis of a round pulmonary mass. A detailed history, especially with regard to occupation and country of origin, is essential. Serological tests for specific Echinococcus antibodies, together with usual imaging procedures, will usually and quickly provide the diagnosis.

摘要

病史及入院检查结果

一名来自哈萨克斯坦的29岁男子,出现右侧胸痛、咳嗽、白色痰液,体温高达38.5摄氏度。他此前两年一直在一家动物农场工作。

检查

实验室检查显示炎症指标升高(白细胞计数15.9×10⁹/L,杆状核和分叶核粒细胞比例增加,C反应蛋白242.3mg/dl)。胸部X线片显示右肺底部有浸润及胸腔积液,判断为肺炎所致。此外,在右下叶第8段胸壁外侧有一个直径2.5厘米的圆形均匀肿块。肺部及纵隔计算机断层扫描(CT)证实了这些发现。支气管镜检查、超声心动图、上腹部超声检查及头颅CT均未发现其他占位性病变。

诊断、治疗及病程:右侧肺炎经治疗成功,起初使用头孢曲松(静脉注射),后来使用氧氟沙星(口服)。鉴于患者来自哈萨克斯坦的职业,在鉴别诊断右侧圆形肿块时特别考虑了棘球蚴囊肿,并通过间接血凝试验确诊,抗体滴度为1:1024。随后进行了开胸手术,切除了组织学检查为棘球蚴囊肿(细粒棘球绦虫)的肿块。未发现其他囊肿。右侧肺炎的病因不明。

结论

尽管棘球蚴病在中欧很少见,但在圆形肺肿块的鉴别诊断中应考虑该病。详细的病史,尤其是关于职业和原籍国的信息至关重要。针对棘球蚴的特异性抗体血清学检测,结合常规影像学检查,通常能快速做出诊断。

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