Heiland S, Sartor K
Abteilung Neuroradiologie, Klinikum der Universität Heidelberg.
Rofo. 1999 Jul;171(1):3-14. doi: 10.1055/s-1999-9889.
Stroke is the third leading cause of death. Until recently, no diagnostic technique was available that could reliably depict ischemic tissue within a therapeutically promising time window. Since the beginning of this decade, a fundamental change has taken place: Perfusion- and diffusion-MRI have shown to be capable of depicting the ischemic injury immediately after vessel occlusion. While perfusion MRI is sensitive to abnormalities in cerebral capillary blood flow (micro-circulation), diffusion MRI indicates tissue damage on a cellular level. Combining perfusion- and diffusion-MRI with standard MR technique (T2-weighted sequences, MR angiography) results in an MR protocol that is complementary and gives insight into both structural and functional parameters.
中风是第三大致死原因。直到最近，还没有一种诊断技术能够在具有治疗前景的时间窗内可靠地描绘出缺血组织。自本世纪初以来，发生了根本性的变化：灌注磁共振成像（MRI）和扩散加权成像已被证明能够在血管闭塞后立即描绘出缺血损伤。灌注MRI对脑毛细血管血流（微循环）异常敏感，而扩散加权成像则在细胞水平上显示组织损伤。将灌注和扩散加权成像与标准MR技术（T2加权序列、磁共振血管造影）相结合，形成了一种互补的MR检查方案，可洞察结构和功能参数。
