McConnell L M
Stanford Program in Genomics, Ethics, and Society, Palo Alto, CA 94304, USA.
Genet Test. 1999;3(1):21-7. doi: 10.1089/gte.1999.3.21.
To assess the potential benefits and risks of genetic testing for Alzheimer disease (AD), patients and families, health care providers, and policymakers must understand the medical and epidemiologic aspects of the disease. This paper provides a brief overview of the symptoms, progression, and etiology of AD, as well as of the prevalence and incidence of the disease. The established and the controversial risk factors thought to be associated with the development of AD are described. Current methods for diagnosing and treating AD are also reviewed.
为评估阿尔茨海默病（AD）基因检测的潜在益处和风险，患者及其家属、医疗保健提供者和政策制定者必须了解该疾病的医学和流行病学方面。本文简要概述了AD的症状、进展、病因以及该疾病的患病率和发病率。文中还描述了被认为与AD发生相关的既定风险因素和有争议的风险因素。同时也对AD目前的诊断和治疗方法进行了综述。
