Schwaiger M, Melin J
Nuklearmedizinische Klinik und Poliklinik, Klinikum rechts der Isar der Technische Universität München, Germany.
Lancet. 1999 Aug 21;354(9179):661-6. doi: 10.1016/S0140-6736(99)06057-2.
Cardiovascular mortality is falling in most industrialised nations. Primarily responsible for this encouraging trend are preventive measures such as risk-factor modification but improved medical and surgical management have helped too. Clinical decision making in the patient with coronary heart disease demands techniques that not only describe coronary anatomy but also provide functional indices for early detection and to monitor the severity and extent of disease. Nuclear medicine methods can characterise non-invasively myocardial function, perfusion, and metabolism. Novel radiopharmaceuticals, improvements in imaging equipment, and extensive validation have contributed to the growing clinical acceptance of these techniques and to their cost-effective integration in the workup of patients with cardiovascular disease.
在大多数工业化国家，心血管疾病死亡率正在下降。促成这一令人鼓舞趋势的主要原因是诸如风险因素调整等预防措施，但医疗和手术管理的改善也起到了帮助作用。冠心病患者的临床决策需要的技术不仅能描述冠状动脉解剖结构，还能提供功能指标以进行早期检测并监测疾病的严重程度和范围。核医学方法可以非侵入性地表征心肌功能、灌注和代谢。新型放射性药物、成像设备的改进以及广泛的验证，促使这些技术在临床上越来越被接受，并在心血管疾病患者的检查中实现了具有成本效益的整合。
