Yamamoto T, Bain I M, Mylonakis E, Allan R N, Keighley M R
University Dept. of Surgery, Queen Elizabeth Hospital, Birmingham, UK.
Scand J Gastroenterol. 1999 Jul;34(7):708-13. doi: 10.1080/003655299750025921.
The aim of this retrospective study was to compare complications and anastomotic recurrence rates after stapled functional end-to-end versus conventional sutured end-to-end anastomosis after ileocolonic resection in Crohn disease.
Between 1988 and 1997, 123 patients underwent ileocolonic resection for Crohn disease. Forty-five patients underwent stapled functional end-to-end anastomosis (stapled group), and 78 underwent sutured end-to-end anastomosis (sutured group).
The stapled anastomosis has been more frequently used during the past 3 years; between 1995 and 1997 it was used in 33 (83%) of 40 patients, compared with only 12 (14%) of 83 patients between 1988 and 1994. There was one anastomotic leak (2%) in the stapled group, compared with six (8%) in the sutured group. The overall complication rate was significantly lower in the stapled group (7% versus 23%, P = 0.04). In the stapled group only one patient required reoperation for ileocolonic anastomotic recurrence, compared with 26 in the sutured group. The cumulative 1-, 2- and 5-year rates for ileocolonic recurrences requiring surgery in the stapled group were 0%, 0%, and 3%, which were significantly lower than the 5%, 11%, and 24% in the sutured group (P = 0.007 by log-rank test).
Although the follow-up duration was short in the stapled group, these results suggest that stapled functional end-to-end ileocolonic anastomosis is associated with a lower incidence of complications and that early anastomotic recurrence is less common than after sutured end-to-end anastomosis. However, a randomized trial would be necessary to draw clear conclusions.
这项回顾性研究的目的是比较克罗恩病患者回结肠切除术后,吻合器功能性端端吻合与传统端端缝合吻合的并发症及吻合口复发率。
1988年至1997年间,123例患者因克罗恩病接受回结肠切除术。45例患者接受吻合器功能性端端吻合(吻合器组),78例接受端端缝合吻合(缝合组)。
在过去3年中,吻合器吻合的使用更为频繁;1995年至1997年间,40例患者中有33例(83%)使用了吻合器吻合,而1988年至1994年间,83例患者中仅有12例(约14%)使用。吻合器组有1例吻合口漏(2%),而缝合组有6例(8%)。吻合器组的总体并发症发生率显著更低(7%对23%,P=0.04)。吻合器组只有1例患者因回结肠吻合口复发需要再次手术,而缝合组有26例。吻合器组需要手术的回结肠复发的1年、2年和5年累积发生率分别为0%、0%和3%,显著低于缝合组的5%、11%和24%(对数秩检验P=0.007)。
尽管吻合器组的随访时间较短,但这些结果表明,吻合器功能性端端回结肠吻合的并发症发生率较低,且早期吻合口复发比端端缝合吻合少见。然而,需要进行随机试验才能得出明确结论。