Reynolds Ian S, Doogan Katie L, Ryan Éanna J, Hechtl Daniel, Lecot Frederik P, Arya Shobhit, Martin Sean T
Department of Colorectal Surgery, St. Vincent's University Hospital, Dublin, Ireland.
Front Surg. 2021 Dec 17;8:804137. doi: 10.3389/fsurg.2021.804137. eCollection 2021.
Postoperative recurrence after ileocaecal resection for fibrostenotic terminal ileal Crohn's disease is a significant issue for patients as it can result in symptom recurrence and requirement for further surgery. There are very few modifiable factors, aside from smoking cessation, that can reduce the risk of postoperative recurrence. Until relatively recently, the surgical technique used for resection and anastomosis had little or no impact on postoperative recurrence rates. Novel surgical techniques such as the Kono-S anastomosis and extended mesenteric excision have shown promise as ways to reduce postoperative recurrence rates. This manuscript will review and discuss the evidence regarding a range of surgical techniques and their potential role in reducing disease recurrence. Some of the techniques have been shown to be associated with significant benefits for patients and have already been integrated into the routine clinical practice of some surgeons, while other techniques remain under investigation. Current techniques such as resection of the mesentery close to the intestine and stapled side to side anastomosis are being challenged. It is looking more likely that surgeons will have a major role to play when it comes to reducing recurrence rates for patients undergoing ileocaecal resection for Crohn's disease.
对于因纤维狭窄型回肠克罗恩病而行回盲部切除术后的患者而言,术后复发是一个重大问题,因为这可能导致症状复发以及需要再次手术。除戒烟外,几乎没有可改变的因素能够降低术后复发风险。直到最近,用于切除和吻合的手术技术对术后复发率几乎没有影响。诸如Kono-S吻合术和扩大系膜切除术等新型手术技术已显示出有望降低术后复发率。本文将回顾并讨论有关一系列手术技术及其在降低疾病复发方面潜在作用的证据。其中一些技术已被证明对患者有显著益处,并且已经被一些外科医生纳入常规临床实践,而其他技术仍在研究中。诸如靠近肠管切除系膜和吻合器侧侧吻合等现有技术正受到挑战。在降低因克罗恩病而行回盲部切除术患者的复发率方面,外科医生似乎将发挥主要作用。