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N-terminus truncated beta-amyloid peptides and C-terminus truncated secreted forms of amyloid precursor protein: distinct roles in the pathogenesis of Alzheimer's disease.

作者信息

Geddes J W, Tekirian T L, Mattson M P

机构信息

Sanders-Brown Center on Aging and Department of Anatomy and Neurobiology, University of Kentucky, Lexington 40536-0230, USA.

出版信息

Neurobiol Aging. 1999 Jan-Feb;20(1):75-9; discussion 87. doi: 10.1016/s0197-4580(99)00012-3.

DOI:10.1016/s0197-4580(99)00012-3
PMID:10466897
Abstract
摘要

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Prediction of Cerebral Amyloid Pathology Based on Plasma Amyloid and Tau Related Markers.基于血浆淀粉样蛋白和tau相关标志物预测脑淀粉样病变
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Novel Phosphorylation-State Specific Antibodies Reveal Differential Deposition of Ser26 Phosphorylated Aβ Species in a Mouse Model of Alzheimer's Disease.新型磷酸化状态特异性抗体揭示了阿尔茨海默病小鼠模型中Ser26磷酸化Aβ物种的差异沉积。
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Structures of Abeta-related peptide--monoclonal antibody complexes.
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C-terminal fragments of amyloid-beta peptide cause cholinergic axonal degeneration by a toxic effect rather than by physical injury in the nondemented human brain.
Neurochem Res. 2003 Apr;28(3-4):493-8. doi: 10.1023/a:1022813104905.