Garrido L, Young V L
Biomaterials Laboratory, NMR Center, Department of Radiology, Massachusetts General Hospital and Harvard Medical School, Charlestown, Massachusetts, USA.
Magn Reson Med. 1999 Sep;42(3):436-41. doi: 10.1002/(sici)1522-2594(199909)42:3<436::aid-mrm5>3.0.co;2-i.
The amount of silicone (polydimethylsiloxane [PDMS]) in capsular tissue surgically removed from women with breast implants was measured by using (29)Si and (1)H magic-angle spinning solid-state NMR spectroscopy. Twelve women having smooth surface silicone gel-filled implants, including a subject with "low-bleed" double-lumen implants, had detectable levels of PDMS ranging from 0. 05 to 9.8% silicon in wet tissue (w/w). No silicon-containing compounds other than PDMS were detected. No correlation was found between the amount of PDMS measured in the capsular tissue and the length of implantation time (Pearson correlation coefficient, r = 0. 22). The results showed no relationship between higher amounts of PDMS and capsular contracture (p = 0.74) or other symptoms (p = 0. 53). Magn Reson Med 42:436-441, 1999.
采用（29）Si和（1）H魔角旋转固态核磁共振波谱法，测定了从植入乳房假体的女性患者手术切除的包膜组织中的硅酮（聚二甲基硅氧烷[PDMS]）含量。12名植入表面光滑的硅胶填充假体的女性，包括1名植入“低渗漏”双腔假体的患者，其湿组织（w/w）中可检测到的PDMS水平为0.05%至9.8%的硅。未检测到除PDMS以外的含硅化合物。在包膜组织中测得的PDMS量与植入时间长短之间未发现相关性（Pearson相关系数，r = 0.22）。结果表明，较高含量的PDMS与包膜挛缩（p = 0.74）或其他症状（p = 0.53）之间无关联。《磁共振医学》42:436 - 441，1999年。
