Juran N B, Rouse C L, Smith D D, O'Brien M A, DeLuca S A, Sigmon K
Cleveland Clinic Foundation, Ohio, USA.
Am J Crit Care. 1999 Sep;8(5):303-13.
This trial is the first prospective, multicenter clinical nursing trial conducted to measure the effect of nursing interventions on bleeding at the femoral access site after percutaneous coronary intervention with or without a potent antiplatelet agent given along with heparin and aspirin.
To measure the relationship between nursing interventions and complications at the arterial access site in patients undergoing percutaneous coronary interventions and to recommend a standard of care to minimize bleeding complications.
In a descriptive, correlational 4010-patient study, nursing care interventions after coronary procedures were measured. Observed standards of care were assessed, and regression techniques were used to evaluate nursing interventions and the effect of the interventions on bleeding at the access site after percutaneous coronary procedures.
Several significant correlations between nursing interventions and the occurrences of moderate to severe bleeding at the access site were found; however, most interventions had little effect. The most significant factors in decreasing complications at the access site were early removal of the arterial sheath, the type of pressure mechanism used to achieve arterial hemostasis, staffing allocation, and the person and method used to remove the sheath.
Many nursing interventions after percutaneous coronary intervention have become routine in the absence of clinical outcome data. Most nursing interventions aimed at decreasing bleeding at the vascular access site increase nursing workload but do not significantly affect bleeding in the groin. These results underscore the importance of continued clinical research studies to validate nursing practice on the basis of patients' outcomes.
本试验是第一项前瞻性、多中心临床护理试验,旨在测量护理干预对经皮冠状动脉介入治疗后股动脉穿刺部位出血的影响,无论是否同时使用强效抗血小板药物以及肝素和阿司匹林。
测量经皮冠状动脉介入治疗患者护理干预与动脉穿刺部位并发症之间的关系,并推荐一种护理标准以尽量减少出血并发症。
在一项描述性、相关性的4010例患者研究中,对冠状动脉手术后的护理干预措施进行了测量。评估了观察到的护理标准,并使用回归技术评估护理干预措施以及这些干预措施对经皮冠状动脉手术后穿刺部位出血的影响。
发现护理干预措施与穿刺部位中度至重度出血的发生率之间存在若干显著相关性;然而,大多数干预措施效果甚微。减少穿刺部位并发症的最重要因素是尽早拔除动脉鞘管、用于实现动脉止血的压迫方式类型、人员配置以及拔除鞘管的人员和方法。
在缺乏临床结果数据的情况下,经皮冠状动脉介入治疗后的许多护理干预措施已成为常规操作。大多数旨在减少血管穿刺部位出血的护理干预措施增加了护理工作量,但对腹股沟部位的出血没有显著影响。这些结果强调了持续进行临床研究以根据患者结果验证护理实践的重要性。