Mosconi G, Mambelli E, Zanchelli F, Isola E, Perna C, De Pascalis A, Raimondi C, Ventrucci M, Stefoni S
Department of Clinical Medicine and Applied Biotechnology, S. Orsola University Hospital, Bologna, Italy.
Int J Artif Organs. 1999 May;22(5):313-6.
Gastrointestinal bleeding is a frequent complication in hemodialysis patients; angiodysplasia is a potential cause, with a higher incidence in uremic patients. We describe a case of severe anemia (Hemoglobin up to 3.5 g/dl) secondary to diffuse angiodysplastic lesions in a hemodialysis patient with mixed connective tissue disease. The case is characterised both by the severity of the clinical picture (extension and entity of angiodysplastic lesions, frequency of bleeding episodes) and by the patient's religious faith which made her reject blood transfusions. We underline the efficacy of estrogen-progesterone therapy in view of the modest results obtained with other therapeutic strategies on bleeding.
胃肠道出血是血液透析患者常见的并发症；血管发育异常是一个潜在原因，在尿毒症患者中发病率更高。我们描述了一例患有混合性结缔组织病的血液透析患者，因弥漫性血管发育异常病变继发严重贫血（血红蛋白低至3.5g/dl）的病例。该病例的特点在于临床表现的严重性（血管发育异常病变的范围和程度、出血发作频率）以及患者因宗教信仰拒绝输血。鉴于其他治疗策略在治疗出血方面效果不佳，我们强调雌激素 - 孕激素疗法的有效性。
