DeLoughery T G
Hematology OP 28, Oregon Health Sciences University, Portland 97201-3098, USA.
Curr Opin Hematol. 1999 Sep;6(5):329-33. doi: 10.1097/00062752-199909000-00010.
Bleeding can complicate the clinical course of both liver disease and uremia. The pathogenesis of bleeding in both syndromes is complex. A variety of options are available for treatment of uremic bleeding including desmopressin, erythropoietin, and estrogens. Bleeding complications of liver disease reflect the importance of this organ for the production of both coagulation factors and thrombopoietin. Careful assessment of both the patient's clinical situation and laboratory findings is important for tailoring therapy of the bleeding patient.
出血会使肝病和尿毒症的临床病程复杂化。这两种综合征出血的发病机制都很复杂。治疗尿毒症性出血有多种选择,包括去氨加压素、促红细胞生成素和雌激素。肝病的出血并发症反映了该器官在凝血因子和血小板生成素产生方面的重要性。仔细评估患者的临床情况和实验室检查结果对于为出血患者量身定制治疗方案很重要。