de Visscher J G, Schaapveld M, Grond A J, van der Waal I
Department of Oral and Maxillofacial Surgery, Medisch Centrum Leeuwarden, The Netherlands.
Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 1999 Aug;88(2):141-4. doi: 10.1016/s1079-2104(99)70107-1.
Among the histologic features of squamous cell carcinoma of the lower lip, maximum tumor thickness in particular is a predictor of regional nodal metastatic spread and thus an important parameter in treatment planning. The purpose of this study was to investigate the relationship between maximum tumor thickness in punch biopsies and maximum tumor thickness in subsequent surgical specimens.
This retrospective study examined the relationship between maximum tumor thickness in punch biopsies with that in subsequent surgical specimens obtained in 72 patients with clinical stage I squamous cell carcinoma of the lower lip.
A correlation between maximum tumor thickness in punch biopies and in subsequent surgical specimens was found only for tumors with a thickness less than 3 mm.
Reliable predictive information could be obtained from punch biopsies with a maximum tumor thickness less than 3 mm. When the maximum tumor thickness exceeds 3 mm, better information may be obtained from either a large incisional biopsy or the surgical specimen.
在下唇鳞状细胞癌的组织学特征中，最大肿瘤厚度尤其可作为区域淋巴结转移扩散的预测指标，因此是治疗规划中的一个重要参数。本研究的目的是调查穿刺活检中的最大肿瘤厚度与后续手术标本中的最大肿瘤厚度之间的关系。
这项回顾性研究调查了72例临床I期下唇鳞状细胞癌患者穿刺活检中的最大肿瘤厚度与后续手术标本中的最大肿瘤厚度之间的关系。
仅在厚度小于3毫米的肿瘤中，发现穿刺活检中的最大肿瘤厚度与后续手术标本中的最大肿瘤厚度之间存在相关性。
对于最大肿瘤厚度小于3毫米的穿刺活检，可获得可靠的预测信息。当最大肿瘤厚度超过3毫米时，通过大切口活检或手术标本可能会获得更好的信息。
